Four chronic diseases account for 63% of severe disease from covid19. Obesity—Diabetes—Hypertension—Heart failure. The report makes sense based on the underlying intracellular pathogens and parasites that cause each of these four diseases. Intracellular pathogens and debris from these pathogens can cohabit intracellularly with viruses, in endothelium, epithelium and stroma. Intracellular pathogens and parasites can also provide a host for a virus. When a pathogen is inside a cell or parasite it is difficult for the immune system to reach…..
The immune system has difficulty fighting intracellular pathogens; and in response to intracellular pathogens and the abnormal proteins generated by the pathogens, the immune system generates a cascade of immune defenses, i.e. the war within, which include a high level of inflammation and generation of adhesion molecules. The immune system attack may be diagnosed as a chronic disease; an autoimmune disease; or in acute disease, as the immune system generating a higher level of damaging inflammation, for unknown reasons. …..
Viruses can only survive and multiply inside a cell or pathogen. Viruses can invade human cells previously infected with intracellular bacteria, and can also invade and become a bacteriophage of other bacterial pathogens. Chronic intracellular infections cause chronic disease. When patients with chronic disease develop covid19 the risk for severe disease and virus variants increases. Intracellular co-infections can confuse the immune system; hide the virus; and trigger an increased inflammatory response, to fight a virus inside a bacteria inside a…..
Viruses are a string of proteins encapsulated by a membrane, which become intracellular to duplicate and spread. Inside the cell the virus loses its outer membrane, and duplicates the string of viral proteins with a new outer membrane. When viruses enter cells previously infected with intracellular bacteria, the virus can evolve into new variants due to the mixing of co-infections or due to diminished cell function caused by a chronic intracellular infection. The variation in underlying chronic intracellular infections in…..
Others are now advocating the repurposing of drugs we already have for covid19, while we wait for new antiviral drugs and covid19 vaccines. We previously reported azithromax has both antiviral and anti-inflammatory activity, and can prevent blood clots and heart attacks from a viral infection; and that imervectin may be beneficial in covid19, based on laboratory studies. The NIH has now withdrawn its objection to imervectin for covid19, and takes no position on its use for covid19. We already have…..
Approximately 1% of the U.S. population lives in nursing homes. Approximately 39% of covid19 deaths (101,100) in the U.S. and 6% of all cases of covid19 (724,000) are occurring in nursing homes. Cases in nursing homes are surging daily. Many residents of nursing homes are over the age at which they were fully vaccinated as children, particularly the MMR, because this patient population were adults before the MMR vaccine became available. DPT (DT) boosters should be given every 10…..
We suggested several times (3/21/20, 6/23/20, 8/6/20, 10/18/20) that childhood vaccines may provide cross reactivity, and protection or partial protection against covid19, particularly the MMR and polio vaccine. Childhood vaccinations provide one explanation for why children do not get covid19, are asymptomatic, or are less severely affected. Vaccinations also explain why some countries have had a lower rate of covid19 and covid19 death—the countries that had mass vaccination programs for the MMR. Other scientists are now also reporting childhood vaccinations,…..
The NYT article describes how malaria can silently hibernate inside cells during the dry season, and erupt when provoked by a new malaria infection during the rainy season. Similarly, acute infection with intracellular pathogens can become a chronic infection, which hides silently and evades detection by the immune system for years or decades. An acute infection in addition to a chronic infection can become a more severe acute infection, trigger adverse events, or trigger the eruption of chronic disease. For…..
Coronaviruses are part of the family of rhabdoviruses. The rhabdovirus family includes several viruses for which we already have vaccines or treatment. The list of viruses in the rhabdoviruses family explains why children are having none or less symptoms with coronaviruses—they were vaccinated more recently for related or similar viruses, to wit: MMR, polio, rotovirus, and influenza. Rhabdoviruses include: coronaviruses–Crimean-Congo hemorrhagic fever orthonairovirus–Dengue virus–Ebolavirus–hantaviruses–Hepatitis B virus–human immunodeficiency viruses–Human orthopneumovirus–influenza viruses–Japanese encephalitis virus–Lassa mammarenavirus–Measles morbillivirus–Mumps orthorubulavirus–Norovirus–Poliovirus–Rabies lyssavirus–Rhinoviruses–Rift Valley fever phlebovirus–Rotavirus–Rubella virus–Tick-borne…..
Imervectin is an anti-parasitic, used to treat a variety of intestinal and skin parasites, in humans and animals. WHO considers Imervectin one of the safest and most important drugs in combating the global burden of disease. In The Origin of Disease: The War Within, we said Imervectin was one of the most underutilized drugs in medicine (Chapter 3, Page 67); and on 4/5/20 and 5/7/20, we posted about Imervectin and Covid-19, after laboratory testing suggested Imervectin was effective in killing…..