Tag Archives: Genetic disease
Research into a variety of childhood chronic diseases, including autism, regressive developmental disorders, fragile-X syndrome, childhood epilepsy, cerebral cavernous malformations, and cystic fibrosis, identified genetic abnormalities and abnormal proteins, in the patients’ blood and cerebral spinal fluid. When an abnormal gene is found, research bias favors assuming genetic causes. Pathogens and parasites have also been found in these patients, but assumed to be only an “association”. Immortal pathogens can create, disperse, and cause abnormal proteins, which alter genes and gene…..
Different forms of chlamydia express different types of proteins, to form a chlamydia inclusion that provides protection from the immune system. Chlamydia pathogens may also express different types of abnormal proteins, during different phases of the life cycle. Other types of immortal pathogens are also capable of expressing abnormal proteins to create a membrane to encapsulate the pathogen, and protect the pathogen from the immune system. By definition, proteins expressed or generated by pathogens are abnormal proteins. Chlamydia pathogens inside…..
Chronic chlamydia can change genes and gene signaling, by creating and dispersing abnormal proteins, debris, and cell parts, which attach to and change genes and gene signaling. The genetic changes can then be passed on to the next generation. A genetic abnormality may make the person susceptible to a chronic disease and can be made worse by new infections; however, an increased susceptibility to a particular chronic disease may also be due to co-infections, a long duration of infection, and…..
Research studies found different genetic variants and rare gene variants in the same diseases; and found different genetic mutations in the same diseases on different continents. Researchers found different rare gene variations in common diseases, in different people. Researchers were unable to find common gene variations in various chronic diseases. These findings raise questions about a diagnosis based solely on abnormal genes and/or gene expression, and show the need to diagnose the root causes of genetic changes.
Abnormal genes and abnormal gene expression do exist, and can be acquired or inherited. Bacteria and viruses can change genes or gene expression, and the abnormal genes or gene expression can then be inherited by offspring. Abnormal genes or gene expression may cause a chronic disease; or make a person susceptible to a chronic disease when a triggering event changes the genetic susceptibility into a chronic disease.
Hippocrates suggested the revolutionary idea that diseases had a cause, and were not sent from God. A diagnosis based on a genetic abnormality may be the modern version of the chronic disease was sent from God. Paul Ewald, PhD, an evolutionary biologist, argued if genes caused chronic disease then the chronic disease would be eliminated or reduced in every generation, because all chronic diseases have a genetic cost. Doctors today may attribute chronic disease to a genetic abnormality; however, genetic…..
Human DNA is most similar to chimpanzees. Within three billion nucleotide bases, only about 20,000+ genes make us unique as human beings. Human genes are not static, and change over time. Twenty years after the separation of identical twins, their genes no longer matched! Identifying abnormal genes in chronic disease is often an observation, rather than a diagnosis of the cause.
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