Chlamydia pneumonia, trachoma, and/or psittacosis, independently or as co-infections, can cause fibromyalgia. Chlamydia species infect endothelium, smooth muscles, and microglia, which generates increased TNF-alpha and cytokines. PCR levels for chlamydia pneumonia are higher in patients with fibromyalgia AND chronic fatigue. Chlamydia species deplete energy in the cell, impair oxygen transport across the cell wall, and trigger inflammation—which matches the cellular findings in fibromyalgia.
Fibromyalgia is a complex “autoimmune” disease, describing widespread muscle and skeletal pain, fatigue, cognitive disorders, and “somatic” symptoms (headache, dizziness, gastrointestinal disorders, bladder, sleep disturbances, fatigue, anxiety, and brain-fog). Fibromyalgia patients have increased oxidative stress and neurogenic inflammation (inflammation arising in nervous tissue). Their microglia overproduce TNF-alpha, cytokines, and other chemical substances that trigger pain. They have an altered microbiome, which negatively impacts the gut-brain pain connection, and induces an overreaction to mild sensory stimulus. Fibromyalgia is more common in…..
Chronic chlamydia infection spreads to host cells throughout the body; and as a greater number of cells become infected, a greater number of cells are deprived of the energy and oxygen necessary for cell function, and endothelial damage becomes more widespread. Chlamydia pneumonia can also spread through smooth muscles, and chlamydia DNA has been found in muscles and joints. Chlamydia pathogens infect immune cells attempting to fight the pathogen, causing damage to immune function. When the patient has more than…..