Tag Archives: chronic disease
People do not have immunity to intracellular animal pathogens (chlamydia, estimated up to 350 different species), which do not merge peacefully, in the human body. The pathogens quickly infect host cells, depleting energy inside the cells; infect monocytes and macrophages (the immune system), weakening the immune system and spreading pathogens; generate inflammation from the immune system attack; generate harmful debris, which can alter genes; and disrupt function. Immortal pathogens start a cascade of events which alter the microbiome and mycobiome,…..
A recent NYT article demonstrates the majority of the problem of antibiotic resistance arises from feeding antibiotics to livestock. In Denmark, scientists showed a reduction in antibiotic use in pigs had no effect on productivity, no measurable impact on public health, and no reduction in disease prevalence among animals. In the U.S., livestock consumes 70% of all antibiotics prescribed; and animals are fed critical antibiotics at a rate seven times higher than in Denmark. Federal guidelines now discourage the use…..
Aristotle said, “Other things being equal, the simplest hypothesis possible is the good principle”. William Ockham said when distinguishing between two hypotheses, to “shave away” unnecessary assumptions or “cut apart” two similar conclusions, and favor the hypotheses with the fewest assumptions. Theodore Woodward said, “When you hear hoof beats, think of horses not zebras”, meaning the most obvious diagnosis is the most likely. In more recent times, Hickam’s dictum said, “A man can have as many diseases as he damn well…..
Veterinarians recognize chronic infections with immortal pathogens and parasites cause chronic disease in animals. Our pets and animals have many of the same chronic diseases as humans, including heart disease, lung disease, asthma, allergies, cancer (including lymphoma), epilepsy, endocrine disease, Addison’s disease (adrenal disease), diabetes, arthritis, gastrointestinal disease, liver disease, obesity, reproductive diseases, kidney disease, urinary tract disease, lupus, multiple sclerosis, conjunctivitis, cataracts, blood disorders, immune diseases, HIV (feline immunodeficiency virus), tuberculosis, Lyme disease, influenza, acne, and more. Cats and…..
A 2012 article reported chlamydia trachoma damages the cell wall membranes, and the PARP mechanism for normal cell death (apoptosis)—a hallmark of cancer. PARP inhibitors are effective in treating fast growing and aggressive tumors that thrive in a low oxygen environment—the tumors most resistant to traditional cancer therapy. PARP inhibitors are being used in breast, ovarian, epithelial ovarian, fallopian tube, and peritoneal cancer; and are being studied in colorectal, prostate, and non-small cell lung cancer, and in melanoma. In 2018,…..
Cystic fibrosis is thought to be a genetic defect in the CFTR gene, affecting mucosal epithelial cells; and gastrointestinal disease is a common co-morbid condition. Chlamydia trachoma attacks mucosal epithelial cells and spreads through macrophages. Mucosal epithelial cells are present throughout the body, lining the respiratory tract, gastrointestinal tract, reproductive tract, joints, bladder, and vascular system. Chlamydia trachoma is present in the reproductive tract of approximately 20% of pregnant women. Respiratory trachoma infection is known to occur in infants under…..
Chronic trachoma in men can cause chronic disease. The prostate is an endocrine gland, and a spongy organ, which can host trachoma; and trachoma can become a chronic infection in the prostate and urinary tract. Chlamydia trachoma has been found in semen, including in the semen of donors at fertility clinics. Undiagnosed chronic trachoma can evolve into other chronic diseases. Peyronne’s disease is when the erect penis has a curve, due to fibrous plaque and scar tissue, inside the…..
Pelvic inflammatory disease (PID) is an infection in the female reproductive organs and pelvis; which causes inflammation, scarring, pain, and infertility. In 90% of cases, PID is caused by chlamydia trachoma. Trachoma can also cause endometriosis, a painful condition in which the tissue lining the uterus grows outside the uterus. As trachoma spreads, it causes inflammation, scarring, inclusion cysts, and a sticky environment, which hampers the proper release of an egg from the ovaries, and implantation of a fertilized egg…..
Cystic fibrosis (CF) is thought to be a genetic disease, arising in infants and young children. In CF, the pulmonary epithelial cells are immunologically impaired, and lung tissue produces copious amounts of mucous, pus, and sputum, clogging the lung. CF patients have consolidation of pus in the lower lung, low oxygen levels, microscopic inclusion cysts, scarring in the lung, and co-morbid gastrointestinal disease. The average lifespan of a CF patient is 37 years old. Chlamydia pneumonia was found in CF…..
Doctors are beginning to hypothesize infectious causes of autism. In mice, treatment with antibiotics reduced or eliminated autism, in the fetus and in subsequent births. The fact antibiotics prevented autism in mice strongly suggests bacterial pathogens can cause autism, alone or in combination with other co-infections, an imbalance in the microbiome, and genetic weaknesses. Studies of autistic children showed high levels of TNF-alpha in the spinal fluid, and high levels of cytokines in the blood plasma, suggesting immune dysfunction. TNF-alpha…..