Tag Archives: chronic disease
Co-morbid diseases should be investigated for possible common infectious causes or combinations of infectious causes. A history of acute infections in the patient, family, household animals, and community is necessary, as the triggering acute infectious event may have occurred years or decades before the onset of chronic disease. Co-morbid diseases may be an observation of different stages and/or processes in the evolution of acute disease into chronic disease; and often may be explained by starting with the known effects of…..
When medicine focuses on naming (new) chronic diseases based on symptoms and constellations of symptoms, medicine is creating an infinite list of named chronic diseases and subparts of chronic diseases. Variations in symptoms in people and over time reflect a variation in effect in different people, a progression of the disease, the duration of the chronic disease, or a new observation or thought about the chronic disease at various stages in the evolution of chronic disease. New observations in an…..
Medicine has focused on deconstructing intricate complexities, and now it is time to recognize formerly unrecognized simplicities and patterns, between specialties and between diseases. Acute intracellular infection can become a chronic intracellular infection; and subsequent acute and chronic bacterial and viral infections can also become intracellular. Over time, the mixing of the genetic material of the pathogens inside the cell can lead to cellular fatigue, mutations, and chronic disease. We cannot solve the mysteries of chronic disease until we…..
Alzheimer’s is not the only disease in which deposits of extracellular lipids, proteins, and cellular debris are found. Chlamydia species are known to generate proteins, debris, clumps and plaque, and the type of chlamydia may determine the type and location of plaque—in the heart, brain, and/or eyes, and inside or outside blood vessels and nerve sheaths. Deposits of clumps of proteins, etc., in the retina, are a predictor of AMD. Alzheimer’s, AMD, and cardiac disease are common co-morbid conditions,…..
The prevalence of multiple sclerosis has been increasing; yet, no definitive test is available which proves the diagnosis of MS. Autoimmune disease in which the body attacks itself is an unprovable assumption—the immune system attacks pathogens. Pathogens and the immune system attack on the pathogens generate debris and trigger inflammation. Many pathogens have been associated with the development or exacerbation of MS, including bacteria (Mycoplasma pneumoniae and Chlamydia pneumoniae); Staphylococcus aureus-produced enterotoxins; viruses (Epstein-Barr virus, human herpesvirus, cytomegaly virus); and…..
Medical science has not yet incorporated standards for the routine diagnosis of pathogens in chronic disease; and reliable and available testing for pathogens may not yet exist. PCR testing is available; however, many ignore the significance of IgA and IgG; which is contrary to scientific reporting in “CHLAMYDIA Intracellular Biology, Pathogenesis and Immunity”, reporting chlamydia infection persists and spreads as a chronic infection. Abnormal PCR test results for IgA and IgM indicate chronic infection that continues to spread in the…..
Many medical scientists have proposed infectious pathogens cause chronic disease, or are associated with chronic disease, for decades. Some propose bacteria, viruses, parasites and fungus; and others specifically state chlamydia species, viruses such as EBV and coronavirus, parasites such as toxoplasmosis and Lyme disease, h-pylori, streptococcus, and others. Many note the impact of specific pathogens and co-pathogens, and the overall infectious burden, as accelerating or worsening chronic disease. Chlamydia species are intracellular bacteria that can damage cell function and…..
Koalas are thought to be a source of the original spillover of chlamydia pneumonia to humans; and are known to be heavily infected with immortal intracellular pathogens, including chlamydia pneumonia and chlamydia pecorum. The infectious burden in koalas is damaging fertility, limiting lifespan, and threatening koalas with extinction. Tasmanian devils are similarly heavily infected with immortal intracellular pathogens, and similarly threatened with extinction. When Tasmanian devils bite each other, during courting or battle, the animals can transmit an aggressive form…..
NEW research on the relationship between Cerebral Microbleeds (CMBs) and various chronic #infections AND the #inflammation they drive. We need to pursue the relationship between infectious agents and devastating brain diseases like #alzheimers. All of the main AD suspects are hit in this paper: #herpesviruses #chlamydiapneumoniae #borreliaburgdorferi aka #lyme and others. The idea that chronic pathogenic infection can lead to a number of different disease manifestations (probably due to genetics, load+duration of infection, and other factors) isn’t crazy. We are…..
An exciting new study is testing the relationship between chlamydia pneumonia and Alzheimer’s. The study treated patients with Trichostatin A (TSA), givinostat, and RG108, which are effective on epigenetic mechanisms; and the antibiotic rifampin, to reduce neuro-inflammation. Chronic CP can spread to the brain and cause Alzheimer’s, neuro-inflammation, and epigenetic changes; thus, treatments administered in the study had a neuroprotective effect by treating the offending pathogens, and the inflammation and epigenetic changes induced by the pathogen. https://pubmed.ncbi.nlm.nih.gov/34847172/
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