Four chronic diseases account for 63% of severe disease from covid19. Obesity—Diabetes—Hypertension—Heart failure. The report makes sense based on the underlying intracellular pathogens and parasites that cause each of these four diseases. Intracellular pathogens and debris from these pathogens can cohabit intracellularly with viruses, in endothelium, epithelium and stroma. Intracellular pathogens and parasites can also provide a host for a virus. When a pathogen is inside a cell or parasite it is difficult for the immune system to reach…..
“CHRONIC: The Hidden Cost of the Autoimmune Pandemic and How to Get Healthy Again” is a new book which follows the same themes as our book–chronic disease arises from chronic infection, and the medical system should seek to diagnose the root infectious causes of chronic disease. The authors express many ideas and make many observations similar to those made in our book, about the root causes of chronic disease and the how the medical system works today. “CHRONIC” discusses chronic…..
Viruses can only survive and multiply inside a cell or pathogen. Viruses can invade human cells previously infected with intracellular bacteria, and can also invade and become a bacteriophage of other bacterial pathogens. Chronic intracellular infections cause chronic disease. When patients with chronic disease develop covid19 the risk for severe disease and virus variants increases. Intracellular co-infections can confuse the immune system; hide the virus; and trigger an increased inflammatory response, to fight a virus inside a bacteria inside a…..
The NYT article describes how malaria can silently hibernate inside cells during the dry season, and erupt when provoked by a new malaria infection during the rainy season. Similarly, acute infection with intracellular pathogens can become a chronic infection, which hides silently and evades detection by the immune system for years or decades. An acute infection in addition to a chronic infection can become a more severe acute infection, trigger adverse events, or trigger the eruption of chronic disease. For…..
Others have written about [undiagnosed] chronic infection with immortal bacteria in chronic inflammatory diseases. In this 2016 article, the authors suggest a relationship between chlamydia pneumonia and Alzheimer’s, arthritis, asthma, atherosclerosis, and cancer; and that the innate immune system reacts to chronic infection to cause inflammatory disease. An immortal pathogen, or combinations of immortal pathogens, can cause the same or different diseases in different patients. Immortal pathogens trigger an immune system reaction and an infectious cascade. Specialization in medicine separates…..
The study suggests the coronavirus mutated in Italy, which led to an increased viral load and increased transmissibility, but did not increase the virulence. Italy has a high number of elderly people, who are more like to have chronic underlying infections; and a high rate of rare diseases, which are likely caused by common intracellular pathogens, such as psittacosis, trachoma, or strep. Italians are at higher risk of chronic psittacosis from contact with infected birds; and are also impacted by…..
Every pandemic in history has had the greatest impact on poor and marginalized communities, going back to the Black Death—communities deprived of adequate nutrition, healthcare, and safe housing; and most likely to have chronic underlying conditions. Viral and bacterial co-infection can lead to more severe disease. Patients with chronic chlamydia pneumonia can develop heart problems; patients with chronic strep or other types of chlamydia can develop kidney problems. Influenza patients can develop a stroke months after acute influenza has resolved……
Influenza pandemics have ravaged society over centuries, as each new form of influenza-A bird flu evolved. Many influenza-A pandemics have occurred at or around the time of other disease outbreaks. The first pandemics in the age of microbiology were in 1889-1880 and 1898-1900. The pandemic of 1889-1880, referred to as the Russian or Asiatic flu, came in 3 waves, and is estimated to have killed more than a million people. Scientists attempted to identify the cause of the pandemics retrospectively,…..
The cell uses a positive charge to bring oxygen and sugar across the cell wall membrane, to bring oxygen and energy to the cell. Chlamydia reverses the charge of the cell wall, from positive to negative; consumes ATP energy made by the cell; and when ATP is depleted, consumes sugar, leading to fermentation. We offer some thoughts about co-infection with chronic intracellular bacteria and acute intracellular viruses: Could a change in the charge in the cell wall, from positive…..
Scientists debate whether viruses are alive. A single-stranded RNA virus is a string of dead proteins surrounded by a membrane, with abnormal proteins attached to the surface of the viral membrane to facilitate invasion of a cell. A virus replicates by division, inside a cell, using the energy of the host cell—thus, cannot be killed—it can only be neutralized or reach a dead end in replication with time, treatment, or vaccines. Host cells can be normal cells or other…..