Tag Archives: CCM

Cerebral cavernous malformation (CCM) is a cluster of malformed and tangled blood vessels in the brain, which was previously assumed to be genetic. Patients with CCM can be asymptomatic; or can have long-term health problems, including headaches, epilepsy, stroke, and death. In 2017, a multistate study, in mice, found gram-negative bacteria activated TLR-4; which was the molecular mechanism in endothelial cells that underlies formation of CCM. CCM and Alzheimer’s have similar findings, in the brain—abnormal and tangled blood vessels, neuronal…..

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