Tag Archives: Alzheimer’s
Cerebral cavernous malformation (CCM) is a cluster of malformed and tangled blood vessels in the brain, which was previously assumed to be genetic. Patients with CCM can be asymptomatic; or can have long-term health problems, including headaches, epilepsy, stroke, and death. In 2017, a multistate study, in mice, found gram-negative bacteria activated TLR-4; which was the molecular mechanism in endothelial cells that underlies formation of CCM. CCM and Alzheimer’s have similar findings, in the brain—abnormal and tangled blood vessels, neuronal…..
The scientific evidence is mounting—chlamydia species cause neurodegenerative diseases. Chlamydia pneumonia has repeatedly been linked to Alzheimer’s disease; and chlamydia pneumonia is known to generate beta-amyloid plaque, such as found in Alzheimer’s brains. Chlamydia trachoma has been linked to Parkinson’s disease; and chlamydia trachoma generates excess alpha-synuclein proteins, which is found in Parkinson’s disease. Chlamydia pneumonia and trachoma also generate inclusion cysts and protein aggregates, which are found in Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative diseases. Many chlamydia species…..
Today is World Alzheimer’s Day, and we take this opportunity to share a remarkable website, which has many experts in the field of intracellular pathogens serving its board. The group posts scientific articles supporting chlamydia pneumonia, trachoma, and emerging chlamydia species, as an infectious cause of Alzheimer’s, cardiovascular disease, asthma, arthritis, and multiple sclerosis. The website endorses a broader view of chronic disease, and provides educational information about chlamydia. The intracellular research group, and “The Origin of Disease: The War…..
Chronic infections cause Alzheimer’s. Findings in the brains of Alzheimer’s patients—plaque and tangles, abnormal proteins, and inflammation, are caused by pathogens and the response of the immune system. Chlamydia has been identified and cultured from Alzheimer’ brains, at the location of plaque and tangles, and inside microglia and immune cells. The microbiology of chronic chlamydia infection is consistent with the pathology found in Alzheimer’s brains. Retinal scans (OCTA) can view small blood vessels and measure neuronal loss, in the back…..
A NYT article reported scientists are finding mixed pathology in Alzheimer’s, including plaque, Lewy bodies, and silent stroke, which has made finding causes and cures significantly more difficult. The scientists are struggling to understand these findings and reframe the issues. Dr. Albert Hofman, chairman of the epidemiology department at Harvard, said he was convinced “Alzheimer’s disease is a vascular disease,” and the precipitating factor in Alzheimer’s is diminished blood flow to the brain. The article reported a more optimistic view…..
Medicine has now named a new form of dementia, called limbic-predominant age-related TDP-43 encephalopathy (LATE)—a type of dementia that mimics Alzheimer disease (AD) but is caused by TDP-43 protein deposits in the brain, rather than the beta-amyloid deposits of Alzheimer’s, and primarily affects people older than 80 years. The protein deposits in Parkinson’s, multiple sclerosis, and ALS are thought to be comprised of TDP-43. https://www.medscape.com/viewarticle/912556 More than one pathogen or combination of pathogens can cause the same disease; and an…..
No long-term study has been done to determine whether patients, who were previously treated with low-dose macrolides, cyclines, or quinolones, for acute and/or chronic infection, have a reduced risk of developing Alzheimer’s or Parkinson’s disease. The same immortal pathogens can cause cardiovascular disease; and studies showed patients treated in the prior three years with azithromycin, clarithromycin, or quinolones, for any reason, had a significant reduction in acute heart attack, stroke, and cardiac death. Male patients with cardiac disease and a…..
The Lieber Institute has the largest collection of postmortem brains in the world. The Lieber Institute studies degenerative brain diseases, Alzheimer’s, autism, traumatic brain disorders, PTSD, schizophrenia, bipolar disorder, anxiety disorder, depression, and suicide, by dissecting and examining frozen brains. Anatomical brain changes alone will not reveal the causes of many brain disorders and many mental illnesses. Immortal pathogens survive death, and likely survive being frozen, in that immortal pathogens have been recovered and revived from ancient permafrost and 1000…..
We have 42,000,000 million proteins inside each cell. Chlamydia lives inside the cell; and H-pylori and/or its fragments can become intracellular. The pathogens foster a sticky intracellular environment, causing proteins to stick together and fold into abnormal shapes; and dispersion of abnormal proteins into adjacent tissue, the blood, and lymphatics. In Parkinson’s, Lewy body proteins develop inside the nerve cell, i.e. intracellularly. In Alzheimer’s, clumps of proteins form outside the cells, between the nerves; and the clumps are larger than…..
Alzheimer’s, Parkinson’s, and dementia have existed for thousands of years. Ancient Greek and Roman physicians associated old age with increasing dementia. Egyptian and Ayurveda writings, the Bible, and Galen’s writings described symptoms resembling Parkinson’s. In 1817, Dr. James Parkinson described the symptoms of shaking associated with Parkinson’s. In 1901, Dr. Alois Alzheimer described the mental decline and memory loss of Alzheimer’s, and suggested microorganisms may cause senile plaque. In 1912, Dr. Frederic Lewy described microscopic particles, in the brains of…..