Viruses are a string of proteins encapsulated by a membrane, which become intracellular to duplicate and spread. Inside the cell the virus loses its outer membrane, and duplicates the string of viral proteins with a new outer membrane. When viruses enter cells previously infected with intracellular bacteria, the virus can evolve into new variants due to the mixing of co-infections or due to diminished cell function caused by a chronic intracellular infection.
The variation in underlying chronic intracellular infections in covid19 patients may explain why covid19 attacks differently in different patients, why medications do not act uniformly in every patient, and why covid19 mutations occur. The diagnosis of underlying chronic immortal pathogens in covid19 patients may advance understanding of the evolution of new viral variants, and finding the most effective treatment