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08 May

Disease naming based on findings causes confusion

Carolyn Merchant Blog 2 0

Medicine has now named a new form of dementia, called limbic-predominant age-related TDP-43 encephalopathy (LATE)—a type of dementia that mimics Alzheimer disease (AD) but is caused by TDP-43 protein deposits in the brain, rather than the beta-amyloid deposits of Alzheimer’s, and primarily affects people older than 80 years. The protein deposits in Parkinson’s, multiple sclerosis, and ALS are thought to be comprised of TDP-43. https://www.medscape.com/viewarticle/912556

More than one pathogen or combination of pathogens can cause the same disease; and an immortal pathogen can cause more than one disease. Different immortal pathogens cause and disperse different types of abnormal proteins, infect different types of immune cells, and alter various genes and gene expression. The naming of LATE as a new disease demonstrates the confusion and complexity in medicine and neurology, caused by naming diseases based on symptoms and findings, rather than causes.


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Written by Carolyn Merchant

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