Otto Warburg won the Nobel Prize, in 1931, for proving one of the primary features of cancer cells was the failure of oxygen inspiration. This year, the Nobel Prize in medicine was awarded to three scientists for study of the mechanism by which cells and organs respond to changing oxygen levels. Dr. Kaelin studied Hippel-Lindau disease, a rare genetic cancer, characterized by the profusion of extra blood vessels and an overproduction of EPO. He demonstrated cancer causes the body to make vegF (vessel endothelial growth factor), which stimulates the production of new blood vessels, and an overproduction of EPO (a hormone produced by the kidney to stimulate red blood cell production). Dr. Radcliffe, studied the kidneys and how organs regulate EPO, in response to available oxygen; and Dr. Semenza studied the relationship between genes and EPO. Their findings are believed to have implications for a variety of diseases, including cancer, anemia, heart attacks, and stroke.

Chlamydia pneumonia damages the endothelium in blood vessels and organs; consumes the ATP energy in the cell; damages oxygen transport across the cell wall; triggers new blood vessel formation; generates abnormal proteins, plaque, and heat-shock proteins; and damages apoptosis, generating infinite infected weak replicas of cells. Endothelial damage to the vessels and tubules of the kidney damages the ability of the kidney to maintain the balance of sodium and potassium, and normal blood pressure. The feedback mechanism between the kidney and endocrine system may also sense the level of oxygen in the blood; and when the kidney senses insufficient oxygen, produces EPO to stimulate creation of more red blood cells, to increase oxygen in the blood. Cardiovascular disease and Alzheimer’s are already strongly correlated with chlamydia pneumonia.

Could chlamydia pneumonia and/or other chlamydia species be the explanation for low oxygen inside cells, formation of new blood vessels, and an excess of vegF, which then triggers an excess of EPO?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831610/