Unfortunately infectious causes of chronic disease have been ignored and dismissed. Treatment may be denied in the acute phase of immortal infections in the name of protecting against antibiotic resistance, and by the time a chronic disease occurs the acute disease has long been forgotten. To prevent antibiotic resistance the best way is to reduce antibiotics in animals (80% of usage). It is not too many antibiotics, it is too many of the wrong antibiotics, and lack of adequate diagnosis of the pathogens being treated.